abstract：BACKGROUND AND AIM:Terlipressin has been shown to be effective in the management of hepatorenal syndrome. However, how terlipressin exerts its effect on the renal artery is unknown. The aim of the present study was to assess the effects of terlipressin on systemic, hepatic and renal hemodynamics in cirrhosis. METHODS:...

journal_title：Journal of gastroenterology and hepatology

authors： Narahara Y,Kanazawa H,Taki Y,Kimura Y,Atsukawa M,Katakura T,Kidokoro H,Harimoto H,Fukuda T,Matsushita Y,Nakatsuka K,Sakamoto C

更新日期：2009-11-01 00:00:00

abstract：:The Asia-Pacific Consensus Conference was convened to review and synthesize the most current information on Helicobacter pylori management so as to update the previously published regional guidelines. The group recognized that in addition to long-established indications, such as peptic ulcer disease, early mucosa-asso...

journal_title：Journal of gastroenterology and hepatology

authors： Fock KM,Katelaris P,Sugano K,Ang TL,Hunt R,Talley NJ,Lam SK,Xiao SD,Tan HJ,Wu CY,Jung HC,Hoang BH,Kachintorn U,Goh KL,Chiba T,Rani AA,Second Asia-Pacific Conference.

更新日期：2009-10-01 00:00:00

abstract：:The most common functional disorder of the biliary tract and pancreas relates to the activity of the Sphincter of Oddi. The Sphincter of Oddi is a small smooth muscle sphincter strategically placed at the junction of the bile duct, pancreatic duct, and duodenum. The sphincter controls flow of bile and pancreatic juice...

journal_title：Journal of gastroenterology and hepatology

authors： Toouli J

更新日期：2009-10-01 00:00:00

abstract：:The growing numbers of potential transplant recipients on waiting lists is increasingly disproportionate to the supply of cadaveric donor organs. The hope for the next 20 years is that supply will satisfy demand. This requires both a reduction in indications for the procedure and an increase in the transplants perform...

journal_title：Journal of gastroenterology and hepatology

authors： Perera MT,Mirza DF,Elias E

更新日期：2009-10-01 00:00:00

abstract：:Hepatitis E, caused by infection with hepatitis E virus (HEV), is a common cause of acute hepatitis in areas with poor sanitation. The virus has four genotypes with one serotype: genotypes 1 and 2 exclusively infect humans, whereas genotypes 3 and 4 also infect other animals, particularly pigs. In endemic areas, both ...

journal_title：Journal of gastroenterology and hepatology

authors： Aggarwal R,Naik S

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIM:To present the experience in management of inflammatory liver pseudotumors from a specialist surgical unit and to review the medical literature on this rare manifestation. METHODS:Between 1995 and 2008, four patients were identified with this type of tumor from a total of 108 resected benign liver l...

journal_title：Journal of gastroenterology and hepatology

authors： Milias K,Madhavan KK,Bellamy C,Garden OJ,Parks RW

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Cancer invasion and metastasis are critical events for patient prognosis; however, the most important step in the whole process of lymph node (LN) metastasis in gastric cancer remains obscure. In this study, the significance of cancer cell behaviors, such as cell detachment, stromal invasion and lym...

journal_title：Journal of gastroenterology and hepatology

authors： Kamata I,Ishikawa Y,Akishima-Fukasawa Y,Ito K,Akasaka Y,Uzuki M,Fujimoto A,Morita H,Tamai S,Maehara T,Ogata K,Shimokawa R,Igarashi Y,Miki K,Ishii T

更新日期：2009-09-01 00:00:00

abstract：AIMS:To investigate the relations between the formation of pigment gallstone and the function of the intestinal mucosal barrier, as well as the underlying mechanism. METHODS:Eighty guinea pigs were randomly divided into three groups in which they were respectively given normal diet, gallstone-causing diet, and gallsto...

journal_title：Journal of gastroenterology and hepatology

authors： Su Y,Wu S,Fan Y,Jin J,Zhang Z

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Our aim was to determine associations between metabolic risk factors and erosive esophagitis. METHODS:In this retrospective case-control study, diagnosis of erosive esophagitis was based on the Los Angeles classification. Endoscopic findings in subjects with erosive esophagitis were reviewed by two ...

journal_title：Journal of gastroenterology and hepatology

authors： Chua CS,Lin YM,Yu FC,Hsu YH,Chen JH,Yang KC,Shih CH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with non-alcoholic fatty liver disease (NAFLD) have an increased risk of atherosclerosis and alanine aminotransferase (ALT) is associated with insulin resistance independently of metabolic factors. The aim of the present study was to investigate whether NAFLD patients with ALT elevation had ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang CC,Lin SK,Tseng YF,Hsu CS,Tseng TC,Lin HH,Wang LY,Kao JH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:A lack of published data remains on factors associated with the treatment response to proton pump inhibitors (PPI) in patients with non-erosive reflux disease (NERD). METHODS:Studies on effectiveness of PPI in patients with NERD were identified using the MEDLINE database and manual searches of the available...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Matsuo K,Urabe Y,Fukuhara T,Tanaka S,Yoshihara M,Haruma K,Chayama K

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Thyroid dysfunction is the most common endocrinopathy associated with hepatitis C and its interferon-based treatment. When undergoing treatment, interferon and ribavirin synergize to potently stimulate the immune system in order to eradicate the virus. One of the innocent bystanders in this accentuat...

journal_title：Journal of gastroenterology and hepatology

authors： Tran HA,Malcolm Reeves GE,Gibson R,Attia JR

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) is an emerging problem in the Asia-Pacific region. However, its prevalence and risk factors in Asian (especially South Asian) communities is poorly studied. In this study, the aim was to determine the community prevalence and risk factors for NAFLD among adu...

journal_title：Journal of gastroenterology and hepatology

authors： Dassanayake AS,Kasturiratne A,Rajindrajith S,Kalubowila U,Chakrawarthi S,De Silva AP,Makaya M,Mizoue T,Kato N,Wickremasinghe AR,de Silva HJ

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of platelet-derived growth factor (PDGF) in biliary fibrosis in the setting of bacterial colonization of the biliary tree. We therefore sought to investigate whether exposure to bacterial lipopolysaccharide (LPS) alters PDGF isoform and receptor expression in cultured r...

journal_title：Journal of gastroenterology and hepatology

authors： Kim TH,Moon JH,Savard CE,Kuver R,Lee SP

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIM:Interleukin (IL)-18 level and association of its two promoter gene polymorphisms at -607 C/A and -137 G/C positions were investigated in Iranian patients with gastrointestinal (GI) cancers. METHODS:232 cases of GI cancers and 312 healthy controls were enrolled. Serum level of IL-18 was measured by e...

journal_title：Journal of gastroenterology and hepatology

authors： Haghshenas MR,Hosseini SV,Mahmoudi M,Saberi-Firozi M,Farjadian S,Ghaderi A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND & AIMS:Both medications with beta-blockers and isosorbide-5-mononitrate and endoscopic variceal ligation have been proven plausible in the prevention of variceal rebleeding. However, the relative efficacy and safety of the combined treatment for preventing rebleeding remains unresolved. METHODS:Patients wit...

journal_title：Journal of gastroenterology and hepatology

authors： Lo GH,Chen WC,Chan HH,Tsai WL,Hsu PI,Lin CK,Chen TA,Lai KH

更新日期：2009-06-01 00:00:00

abstract：AIM:To investigate the morphological changes of intratumoral microvessels after administration of thalidomide in occult hepatic metastases. METHODS:Twenty mice with hepatic metastases created by injection of colon-26 tumor cells into the spleen were enrolled. Ten mice were treated with thalidomide (200 mg/kg) by intra...

journal_title：Journal of gastroenterology and hepatology

authors： Liu Y,Li H,Matsui O

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Probucol is a lipid-lowering agent with anti-oxidant effects. Oxidative stress and inflammation are important in the pathophysiology of insulin resistance. We aimed to evaluate the effects of probucol on liver histological changes, serum and hepatic levels of adipokines in rats with high fat-induced...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang X,Li Z,Liu D,Xu X,Shen W,Mei Z

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIM:Studies have shown monounsaturated oleic acid to be less toxic than palmitic acid and to prevent/attenuate palmitic acid hepatocites toxicity in steatosis models in vitro. However, to what degree these effects are mediated by steatosis extent is unknown. METHODS:We evaluated whether steatosis per se...

journal_title：Journal of gastroenterology and hepatology

authors： Ricchi M,Odoardi MR,Carulli L,Anzivino C,Ballestri S,Pinetti A,Fantoni LI,Marra F,Bertolotti M,Banni S,Lonardo A,Carulli N,Loria P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND AIMS:We identified patients with nonalcoholic fatty liver disease (NAFLD) to determine the predictive value of serum markers to diagnose histological steatohepatitis (NASH). METHODS:Demographic, serological, radiological and histological variables on 95 consecutive patients with NAFLD were recorded. The...

journal_title：Journal of gastroenterology and hepatology

authors： Malik R,Chang M,Bhaskar K,Nasser I,Curry M,Schuppan D,Byrnes V,Afdhal N

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIM:The rate of fibrosis progression per year can predict the time for the development of cirrhosis in chronic hepatitis C (CHC). We assessed the rate of fibrosis progression and the predictors of disease severity in Indian CHC patients. METHODS:Of the 355 treatment-naïve, histologically-proven CHC pati...

journal_title：Journal of gastroenterology and hepatology

authors： Hissar SS,Kumar M,Tyagi P,Goyal A,Suneetha PV,Agarwal S,Rastogi A,Sakhuja P,Sarin SK

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIM:In Japan, peptic ulcer disease (PUD) is treated clinically with a combination of a mucosal protectant and acid suppressants, but there is scant information regarding the effects of these drugs on normal gastric mucus cells. In the present study, the effects of co-administration of methylmethionine su...

journal_title：Journal of gastroenterology and hepatology

authors： Ichikawa T,Ito Y,Saegusa Y,Iwai T,Goso Y,Ikezawa T,Ishihara K

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Outer membrane proteins of Helicobacter pylori mediate important pathogen-host interactions such as colonization, adhesion and the inflammatory response. hopQ genotypes have been suggested to be associated with increased risk of peptic ulcer. The aim of this study was to test the relation of hopQ ge...

journal_title：Journal of gastroenterology and hepatology

authors： Ohno T,Sugimoto M,Nagashima A,Ogiwara H,Vilaichone RK,Mahachai V,Graham DY,Yamaoka Y

更新日期：2009-03-01 00:00:00

abstract：:Primary liver cancer, particularly hepatocellular carcinoma (HCC) remains a significant disease worldwide. It is among the top three causes of cancer death in the Asia Pacific region because of the high prevalence of its main etiological agents, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. I...

journal_title：Journal of gastroenterology and hepatology

authors： Yuen MF,Hou JL,Chutaputti A,Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the relationship between human leptin receptor (LEPR) gene G3057A polymorphism and type 2 diabetes mellitus (T2DM) patients complicated with or without non-alcoholic fatty liver disease (NAFLD). METHODS:Two hundred and sixteen cases of newly diagnosed T2DM patients (104 cases complica...

journal_title：Journal of gastroenterology and hepatology

authors： Lu H,Sun J,Sun L,Shu X,Xu Y,Xie D

更新日期：2009-02-01 00:00:00

abstract：:The focus on colorectal neoplasia has led to an exponential increase in the use of colonoscopy in many countries. Although colonoscopy facilitates the diagnosis and treatment of colonic disease, there are public health issues that include access, training, diagnostic accuracy, complications and additions to health-car...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts-Thomson IC,Teo E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIM:Ethnic differences in non-alcoholic steatohepatitis (NASH) are well-documented, but there has been no study on the prognosis of Japanese NASH patients with cirrhosis. Accordingly, we compared cirrhotic NASH with liver cirrhosis caused by chronic hepatitis C (LC-C) to clarify its clinical features and...

journal_title：Journal of gastroenterology and hepatology

authors： Yatsuji S,Hashimoto E,Tobari M,Taniai M,Tokushige K,Shiratori K

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:CYP2C19 polymorphism plays an important role in the metabolism of proton pump inhibitors. The multidrug resistance (MDR)1 genotype is associated with the successful eradication of Helicobacter pylori. The aim of the present study was to investigate the effects of CYP2C19 and MDR1 genotypes on the eradication...

journal_title：Journal of gastroenterology and hepatology

authors： Oh JH,Dong MS,Choi MG,Yoo HW,Lee SB,Park YI,Chung IS

更新日期：2009-02-01 00:00:00

abstract：AIM:To determine the inter-observer agreement and validity of the LA Classification in scoring the severity of esophagitis in Asian patients. METHODS:Video endoscopy clips were selected from 45 consecutive patients participating in reflux studies. The videos were viewed by endoscopists who then independently scored th...

journal_title：Journal of gastroenterology and hepatology

authors： Wong RK,Yeoh KG,Gwee KA,Tay HW,Ho KY

更新日期：2009-01-01 00:00:00

abstract：:High circulating serum immunoglobulin G4 (IgG4) levels have been proposed as a marker of autoimmune pancreatitis (AIP). The aim of the present study was to review the data existing in the English literature on the usefulness of the IgG4 serum levels in the diagnosis and follow up of patients with AIP. A total of 159 p...

journal_title：Journal of gastroenterology and hepatology

authors： Morselli-Labate AM,Pezzilli R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND AIM:There have been few studies in Japan of the utility of quality of life (QOL) questionnaires as an evaluation of chemotherapy for gastrointestinal (GI) cancer. The present study investigated whether QOL can be an indicator of the clinical benefit of chemotherapy, by analyzing the changes in the QOL sc...

journal_title：Journal of gastroenterology and hepatology

authors： Kato J,Nagahara A,Iijima K,Yoshimura M,Osada T,Yoshizawa T,Watanabe S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Enriched blood vessels occur in the stroma of Barrett's esophagus and are related to the ease of tumor invasion in the early stage of the cancer. Hypoxia-inducible factor (HIF) is closely related with angiogenesis through expression of vascular endothelial growth factor. The aim of the present study was to d...

journal_title：Journal of gastroenterology and hepatology

authors： Moriyama N,Amano Y,Mishima Y,Okita K,Takahashi Y,Yuki T,Ishimura N,Ishihara S,Kinoshita Y

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:There are clinical reports that Helicobacter heilmannii, as well as Helicobacter pylori, has been clinically reported to cause gastric low-grade mucosa-associated lymphoid tissue-type (MALT) lymphoma, although its precise mechanism remains to be clarified. Thus, the present study was undertaken to elucidate ...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura M,Takahashi S,Matsui H,Murayama SY,Aikawa C,Sekiya Y,Nishikawa K,Matsumoto T,Yamada H,Tsuchimoto K

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND AIM:Melibiose/rhamnose permeability test is used for noninvasive intestinal mucosa barrier testing. However, the possible escape route of the absorbed saccharides through either intact or impaired blood-biliary barriers has not so far been explored. The objective of the present study was therefore two-fo...

journal_title：Journal of gastroenterology and hepatology

authors： Tomsik P,Sispera L,Rezacova M,Niang M,Stoklasova A,Cerman J,Knizek J,Brcakova E,Cermanova J,Micuda S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. However, there is no general consensus as to which staging system is the most reliable for predicting the survival of patients with HCC. The aims of this study were to compare commonly-used staging systems in a cohort of Chin...

journal_title：Journal of gastroenterology and hepatology

authors： Lu W,Dong J,Huang Z,Guo D,Liu Y,Shi S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of this study was to assess the gastric histopathology and serum gastrin-17 and pepsinogens profiles in patients with duodenal ulcer before and after Helicobacter pylori eradication in a population with a very high prevalence of H. pylori. At the same time we assessed the role of H. pylori de...

journal_title：Journal of gastroenterology and hepatology

authors： Pimanov SI,Makarenko EV,Voropaeva AV,Matveenko ME,Voropaev EV

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND/AIMS:Psychological factors and subtle histopathological changes have been implicated in irritable bowel syndrome (IBS). The aims of the present study were to investigate whether the numbers of enterochromaffin (EC) cells, mast cells, and lamina propria T lymphocytes are altered in IBS, and evaluate the relat...

journal_title：Journal of gastroenterology and hepatology

authors： Lee KJ,Kim YB,Kim JH,Kwon HC,Kim DK,Cho SW

更新日期：2008-11-01 00:00:00

abstract：AIM:To evaluate granulocytapheresis (GCAP) in active ulcerative colitis (UC), with particular attention to the long-term effects of such treatment. METHODS:We included 80 patients with UC. Activity of the disease was evaluated by clinical activity index and endoscopic index. Patients were randomly divided in two group...

journal_title：Journal of gastroenterology and hepatology

authors： Bresci G,Parisi G,Mazzoni A,Scatena F,Capria A

更新日期：2008-11-01 00:00:00

abstract：:Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and eventually cirrhosis. Accumulated data suggest that HCV proteins suppress host immune responses through the suppression of functions of immune...

journal_title：Journal of gastroenterology and hepatology

authors： Hiroishi K,Ito T,Imawari M

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate a possible association between HLA genes with serum alanine aminotransferase (ALT) levels and evaluate whether the HLA-DQA1, DQB1, and DRB1 genes could influence the development of liver damage in chronic hepatitis C. METHODS:A total of 145 patients with chronic hepatitis C virus (HCV...

journal_title：Journal of gastroenterology and hepatology

authors： Yu RB,Hong X,Ding WL,Tan YF,Zhang YX,Sun NX,Wu GL,Zhan SW,Ge DF

更新日期：2008-09-01 00:00:00